Top 10 Healthcare Software Development Companies in Chicago

Nidhi Thakur

27 Feb 2025

Today, technology touches every part of our lives. From the phone or laptop you use right now to the airplane flying overhead, technology is all around us. Every day, new innovations change how we live.

This is especially true in healthcare. New technology is making patient care and diagnosis better. In Chicago, a city known for its strong tech scene and top healthcare centers, hospitals and clinics are looking for digital solutions to work more efficiently and improve patient outcomes. Because of this, there is a high demand for skilled healthcare software development firms.

We have put together a list of the best healthcare software development companies in Chicago. To create this list, we looked at:

• How many years the company has worked in software development
• The number of healthcare projects they have completed
• The technology they use
• Whether their software meets HIPAA standards
• Reviews from clients
• The size and experience of their team

Healthcare Software Landscape in Chicago 2025

Chicago’s healthcare software industry is experiencing remarkable growth and transformation. Recent market research indicates that the sector has grown by approximately 12% annually since 2020, with projected revenues exceeding $5 billion in 2025. Here are some key statistics that illustrate this vibrant landscape:

• Nearly 70% of hospitals in Chicago have integrated electronic health record (EHR) systems, and over 80% have adopted telemedicine and remote patient monitoring solutions.
• The city is home to more than 200 healthcare software startups, driving continuous innovation and creating new job opportunities in the tech and healthcare sectors.
• Venture capital investments in digital health have surged by nearly 50% in recent years, positioning Chicago as one of the top cities in the US for healthcare IT innovation.
• Over 90% of healthcare software solutions developed in Chicago adhere to stringent standards such as HIPAA and GDPR, ensuring robust data security and privacy.

List of Healthcare Software Development Companies in Chicago

After carefully considering the above factors, we have compiled a list of top healthcare software development companies in Chicago.

1. Ditstek Innovations - Leading Healthcare Software Development Company Chicago

Ditstek Innovations is a healthcare software development company that creates scalable and secure digital solutions for the healthcare industry. We work closely with both startups and large enterprises to build next-generation software tailored to each customer's specific needs. With over 7 years of experience, we have built custom medical platforms, fitness and wellness applications, medical imaging solutions, and much more.

Our key services include:

• Healthcare Software Development
• Custom Software Development
• Mobile App Development
• Web Development and Design
• AI Development
• UI/UX Design

In addition, we offer advanced solutions such as telemedicine software, remote patient monitoring systems, patient engagement tools, and Internet of Things (IoT) health software. Our expertise in emerging technologies like IoT, and artificial intelligence helps us deliver cutting-edge healthcare solutions that improve security and scalability.

We proudly serve a wide range of industries including fintech, real estate, edtech, business and workflow automation and many more.

2. Zealous System - Healthcare Software Development Company in Chicago

Based in the United States, Zealous System is a leading healthcare software development company that delivers scalable and secure digital solutions for the healthcare industry. They work closely with healthcare providers to understand each client’s unique needs and develop custom software that improves patient care and streamlines operations.

Key Services:

• Telemedicine software development
• Remote patient monitoring systems
• Patient engagement solutions
• Mobile health app development
• Web development and design

With a strong track record of partnering with hospitals and healthcare organizations, Zealous System helps transform digital processes and improve operational efficiency, allowing providers to focus on delivering quality care.

3. Fortunesoft - Chicago Healthcare Software Development

Fortunesoft is a forward-thinking provider of digital healthcare solutions that transforms how healthcare providers manage their operations. With a commitment to innovation and a deep understanding of the medical industry, Fortunesoft designs custom software that simplifies complex processes and improves patient care.

Their team works hand in hand with healthcare organizations—from hospitals to specialty clinics—to craft solutions that are both robust and scalable. Fortunesoft’s approach emphasizes clear communication, agile development practices, and long-term support, ensuring that each project evolves with the dynamic needs of the healthcare sector.

Key Services:

• Custom Healthcare Software Solutions
• Mobile App Development
• Web Development and Design
• UI/UX Design

By leveraging their expertise, Fortunesoft helps organizations streamline workflows, enhance patient engagement, and ultimately deliver better care. Their focus on continuous improvement and innovation sets them apart as a leader in the digital transformation of healthcare.

4. Appinventive - Custom Healthcare Software Development Company in Chicago

Appinventive is a leading mobile app development company that delivers end-to-end solutions for businesses across various industries, including healthcare. Known for its strong focus on quality and user-friendly design, Appinventive builds innovative mobile applications that help organizations streamline operations and engage their users.

Key Services:

• Custom Mobile App Development
• Healthcare App Design (UI/UX)
• End-to-End Mobile Solutions (from consultation and design to development, testing, and support)
• Integration with healthcare systems (like EHR)
• Agile Development Processes for quick delivery and scalability

With a dedicated team that works closely with clients to understand their unique needs, Appinventive ensures that every solution is tailored to meet specific challenges. Their commitment to speed, security, and quality makes them a trusted partner for both startups and established enterprises looking to innovate in the digital space.

5. AmorServ - Healthcare Software Development Services in Chicago

AmorServ is a US-based healthcare software development company that has gained recognition from respected sources. They serve a wide range of clients—from healthcare providers and medical device manufacturers to educational institutions, life sciences companies, and startups.

They develop both custom and SaaS solutions, offering patient applications (such as telemedicine and remote patient monitoring apps) and administrative software (including EHR, HIE, LIS, and inventory tracking systems).

Key Services:

• Custom Healthcare Software Development
• Mobile and Web Application Development
• System Integration and Legacy Modernization
• UI/UX Design and Prototyping

By working closely with healthcare organizations, AmorServ ensures that every solution is tailored to fit seamlessly into the client’s operations, driving efficiency and innovation in a constantly evolving digital world.

6. Grapelime - Leading Healthcare Software Development Company Chicago

Grapelime is a top healthcare software development company based in Chicago, known for crafting custom digital solutions that meet the unique needs of healthcare providers. They begin every project with a thorough discovery process to fully understand client requirements, then move on to design, development, and rigorous testing to ensure a secure and scalable product.

Their experienced team focuses on delivering solutions that streamline operations and enhance patient care, making Grapelime a trusted partner for healthcare organizations looking to modernize their digital systems.

Key Services:

• Healthcare CRM Development
• Custom Web Application Development
• Mobile App Development
• UI/UX Design
• Quality Assurance & Testing
• Cloud Solutions & Integration
• Enterprise Software Consulting
• Ongoing Support and Maintenance

7. Slingshot - Healthcare Software Development Company in Chicago

Since 2005, Slingshot has been a one-stop provider for healthcare app and software development in Chicago, working with organizations ranging from mid-sized healthcare companies to nationwide institutions.

They guide projects from the initial idea through in-depth research, design, testing, and launch. Protecting patient data and improving patient outcomes are top priorities for Slingshot. With a strong understanding of HIPAA, they have built secure healthcare solutions—including a mobile app for clinicians to diagnose child abuse, provider credentialing apps, and telemedicine platforms.

Slingshot’s process focuses on a deep understanding of the user to ensure every product is:

Certified: SOC 2 and HITECH compliant, meeting HIPAA standards
Secure: Prioritizing privacy, security, and compliance
Beautiful: Designed with aesthetic appeal to keep users engaged and elevate your brand
Intuitive: Transforming complex ideas into easy-to-use products

Key Services:

• Healthcare App Development
• Mobile App Development for Clinicians
• Telemedicine Platform Development
• Provider Credentialing Application Development
• End-to-End Digital Solution Delivery

Their commitment to a meticulous and user-focused approach makes Slingshot a trusted partner for healthcare organizations looking to modernize their digital solutions

8. Intersog - Custom Healthcare Software Development Company in Chicago

Intersog is a professional healthcare software development agency based in Chicago, USA. They leverage the latest innovations in eHealth to improve the performance of medical professionals and enhance patient quality of life. By addressing key challenges like device safety, data integrity, and reliable, timely data communication, Intersog develops custom eHealth solutions that reduce the need for human supervision and support efficient operations in medical facilities.

Intersog offers full-cycle, customized development services—from the ideation stage to implementation and ongoing support. They help create personalized patient experiences with solutions ranging from simple booking systems to complex mobile healthcare applications. Their work also focuses on streamlining internal processes, managing equipment and staff, and enabling better collaboration between medical professionals and patients, both on-site and remotely. Additionally, they build HIPAA-compliant solutions to ensure data security and regulatory compliance.

Key Services:

• Custom Healthcare Software Development
• Mobile and Web Healthcare Applications
• End-to-End eHealth Solution Delivery
• Personalized Patient Experience Solutions
• Process Simplification and Workflow Automation
• Secure, HIPAA-Compliant Application Development

9. Flatirons Development - Healthcare Software Development Company for Chicago

Flatirons Development specializes in creating custom healthcare software solutions designed to improve patient care and streamline operations. They offer a comprehensive suite of services tailored specifically for the healthcare sector, working with businesses ranging from startups to Fortune 100 enterprises. With an average client relationship of 3 years and a perfect Clutch client rating of 5.0, Flatirons has earned more than 50 industry awards for its work.

They develop a variety of healthcare solutions, including EHRs, telemedicine apps, and health management systems. Flatirons follows a structured approach—from the initial consultation through to project delivery and ongoing support—to ensure that every solution meets client needs and industry standards.

Key Services:

• Custom Healthcare Software Development
• EHR System Development
• Telemedicine Application Development
• Health Management System Solutions
• End-to-End Project Delivery and Support

10. SOFTERMII - Healthcare Software Development Company in Chicago

SOFTERMII is a dedicated healthcare software provider that partners with healthcare providers, organizations, and startups to build modern mHealth applications and telemedicine software. They help take your digital healthcare infrastructure to the next level by offering solutions for patients, physicians, and staff management, along with seamless EHR integration.

With a specialized team comprising over 100 developers, project managers, and QA specialists, SOFTERMII follows flexible and agile software development practices. Their solutions are secure and compliant with key standards such as HIPAA, GDPR, HL7, SOC2, and local privacy regulations. SOFTERMII’s experts continually update their skills and conduct market research to ensure they deliver relevant, cutting-edge healthcare solutions.

Key Services:

• mHealth Application Development
• Telemedicine Software Development
• Patient-Facing App Development
• Physician App Development
• Healthcare Staff Management Solutions
• EHR Integration

Conclusion

The healthcare software landscape in Chicago is thriving, driven by innovation, collaboration, and a commitment to improving patient outcomes. Our blog has highlighted top companies—each with unique strengths and specialized services—that are transforming how healthcare providers deliver care. From custom mobile and web applications to secure, scalable digital solutions, these firms are setting new benchmarks for efficiency, compliance, and user experience.

With increasing investments, rising adoption rates of advanced digital tools, and a robust ecosystem of startups and established players, Chicago is poised to remain at the forefront of healthcare technology in 2025 and beyond. Whether you’re a startup or a large healthcare organization, partnering with these leading firms is a key step toward a more innovative, efficient, and patient-centered future.

FAQs

Why is Chicago a hub for healthcare software development?

Chicago has a strong tech ecosystem, top healthcare institutions, and a vibrant startup culture. This combination drives innovation and attracts significant investments in digital health solutions.

What should I look for when choosing a healthcare software development partner?

Key factors include the company's experience, portfolio of healthcare projects, technology stack, compliance with regulations (like HIPAA), client reviews, and team expertise.

How do these companies ensure data security and compliance?

Most companies follow strict protocols and standards, such as HIPAA and GDPR, and often use secure cloud solutions and regular audits to protect sensitive patient data.

Can these companies develop both custom and SaaS solutions?

Yes, many healthcare software development firms offer both custom solutions tailored to individual needs and scalable SaaS products to serve a wider range of clients.